The Position

In Roche´s Pharmaceutical Research and Early Development organization (pRED), we make transformative medicines for patients in order to tackle some of the world's toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.

The position is located in preclinical Chemistry, Manufacturing and Controls, a department within the Therapeutic Modalities function, where the development of robust and innovative API synthesis and drug products to supply and enable key preclinical activities paves the way towards Entry into Human. We are CMC experts and together with our discovery functions partners, we generate scientific and technical knowledge to assess the developability of drug candidates. We build our strength on a broad diversity of enthusiastic technical experts, pharmacists, chemists and analytical chemists delivering and innovating in the space of small molecules, peptides and oligonucleotides.

As an Intern in Oligonucleotide Process Chemistry, you will become a key player in the development of next-generation methodologies for the production and characterization of highly complex oligonucleotides. You will have the opportunity to work with the latest state of the art laboratory and analytical equipment as well as with new technologies.

As an Intern in our team your main tasks will include:

• Discovery of new techniques for the synthesis of complex oligonucleotides.
• Scale up of your findings into processes for the preparation of multi-gram quantities of desired target materials.

Purification and analysis of reactions involving oligonucleotides with state of the art chromatographic techniques.

Who You Are:

• An enthusiastic, motivated and scientifically interested person who enjoys teamwork and has a strong willingness to learn new techniques.
• Preferably a chemistry/biochemistry student with prior lab experience.
• Prior experience with oligonucleotide chemistry (solid phase synthesis, conjugation, purification and analysis) is desirable.
• Excellent organizational skills and proactive knowledge sharing.
• Excellent written and verbal communication skills in English.

Desired start date: October 2022

Workload: 100%

Duration: 6-12 months

Have we piqued your interest? Then we look forward to receiving your complete application documents (letter of motivation, CV, job references, diplomas, etc.).Please clearly indicate your preferred starting date and duration (6 to 12 months) of internship on your application motivational letter. 

Please note that this internship is not suitable for a thesis.

Due to regulations, non-EU/EFTA citizens have to provide a certificate from the university stating that an internship is mandatory as part of the application documents.

Who we are

At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more.

Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.

We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.

Roche is an Equal Opportunity Employer.