Postdoctoral Scientist in Personalized Safety (start June 2021, 2 years)

 

At Roche, we believe it's urgent to deliver medical solutions right now - even as we develop innovations for the future. We are passionate about transforming patients' lives and we are fearless in both decision and action. And we believe that good business means a better world. That is why we come to work every single day. We commit ourselves to scientific rigour, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow.

The position

Pharmaceutical Sciences (PS) is a global function within Roche Pharma Research and Early Development (pRED) which covers several research areas including Immunosafety. As part of the the Immunosafety group you will work in close collaboration with scientists from different departments within PS/pRED to generate and integrate molecular, cellular, tissue and functional data with the goal of delivering unique and holistic insights into personalized drug safety and enable informed decisions to bring the best drugs to patients.

In this position you will develop and/or apply innovative in vitro, in silico and in vivo (mouse) models to better investigate the mechanisms underlying cytokine release syndrome (CRS), identify novel biomarkers and validate their predictive value in clinical trials both retro- and prospectively. 

Who you are

We are looking for a highly motivated postdoctoral scientist who graduated in the last 3 years and has the following expertise:

  • Excellent knowledge of immunology and solid experience in applying this knowledge to answer complex biological questions

  • As the ideal candidate, you have experience with biologics, namely monoclonal antibodies, fusion/bispecific molecules, peptides, and immune-engaging molecules

  • Theoretical and practical knowledge of flow cytometry is a must

  • Practical experience in primary cell culture and in vitro immunoassay (e.g. ELISA, ELISpot, multiplexed immunoassays, etc.) 

  • Experience in the field of cancer immunotherapy and with immuno-oncology in-vivo models is a plus

  • Excellent interpersonal and communication skills and strong attitude to teamwork.

  • Excellent strategic thinking, self-initiative and strong sense of accountability.

  • Ability and willingness to challenge, be challenged and learn. 

  • Strong track record in immunology and/or immunosafety

  • Proficient in spoken and written English

Starting date: The position can start June 2021. Please clearly indicate your preferred start date in your cover letter.

To be considered your application needs to

  • Include a  cover letter, a CV, and a reference letter

Are you ready to apply? We are looking for someone who thinks beyond the job offered - someone who knows that this position can be a rare springboard to many other opportunities at Roche. When applying for this position, already project yourself in the future. Think about what could come next and how you would like to build your future.

Roche embraces diversity and equal opportunity in a serious way. We are dedicated to building a team that represents a range of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.

If you still have questions, then please check our FAQs and videos on careers.roche.ch/faq

Roche
Roche ist ein globales Unternehmen mit Vorreiterrolle in der Erforschung und Entwicklung von Medikamenten und Diagnostika und ist darauf fokussiert, Menschen durch wissenschaftlichen Fortschritt ein besseres, längeres Leben zu ermöglichen. Roche ist das grösste Biotech-Unternehmen weltweit mit differenzierten Medikamenten für die Onkologie, Immunologie, Infektionskrankheiten, Augenheilkunde und Erkrankungen des Zentralnervensystems. Roche ist auch der bedeutendste Anbieter von In-vitro-Diagnostika und gewebebasierten Krebstests und ein Pionier im Diabetesmanagement. Dank der Kombination von Pharma und Diagnostika unter einem Dach ist Roche führend in der Personalisierten Medizin – einer Strategie mit dem Ziel, jedem Patienten die bestmögliche Behandlung zukommen zu lassen.
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